Application

Research CategoryMetabolism

Research Sub CategoryObesityMetabolic Disorders

Biochem/physiol Actions

Target Sub-Family: STE

Protein Target: Cot1

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Product Source: Human Cot1, amino acids 30-397, expressed by baculovirus in Sf21 insect cells.

N-terminal 6His-tagged recombinant human Cot1, amino acids 30-397.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Physical form

Ni²⁺/NTA-agarose

Quality

routinely evaluated by activation of MEK1 (14-420). The activated MEK1 was used to activate MAPKinase 2/Erk2, unactive. Subsequent phosphorylation of MBP (13-104) was performed.

Storage and Stability

6 months at -70°C from date of shipment